Antibacterial activity and characterization of extracts from pot-grown Kalanchoe leaves (daigremontiana and tubiflora)
Keywords:
Medicinal plants, leaf extract, Kalanchoe, antibacterial activityAbstract
Currently, researchers in the health area face a great challenge in the control of various diseases that affect humans, generating great interest in studying the diversity of medicinal plants beneficial to health, such as Kalanchoe (daigremontiana and tubiflora). The objective of the study was to evaluate the characterization and antibacterial activity of extracts from Kalanchoe leaves (daigremontiana and tubiflora) grown in pots. They were evaluated by direct observation and assessment according to descriptors for leafy succulent plants (IBPGR-IPGRI-BIOVERSITY). Antimicrobial testing of ethanolic extracts of Kalanchoe daigremontiana and Kalanchoe tubiflora grown in pots showed great potential for inhibitory activity against E. coli, Staphylococcus aureus, Salmonella enterica and Pseudomonas aeruginosa, including both Gram-positive and Gram-negative bacteria. Significant differences were found compared to the aqueous extracts (α = 0.05). Ethanolic extracts of both Kalanchoe varieties could be a natural means to treat ailments related to these bacteria. Both Kalanchoe species possess phenolic compounds with antioxidant properties, making them a promising source of beneficial effects.
Downloads
References
Arnao, M. B., Cano, A., & Acosta, M. (2001). The hydrophilic and lipophilic contribution to total antioxidant activity. Food Chemistry, 73(2), 239–244. https://doi.org/10.1016/S0308-8146(00)00324-1
Báez, M., Torres, E. I., Gruszycki, A. E., Andrés Alba, D., Valenzuela, G. M., & Gruszycki, M. R. (2021). Actividad antioxidante y antiinflamatoria en extractos hidroalcohólicos de Kalanchoe daigremontiana Raym. -Hamet & H. Perrier. Revista Colombiana de Ciencias Químico-Farmacéuticas, 50(1). https://doi.org/10.15446/rcciquifa.v50n1.95450
Bogucka-Kocka, A., Zidorn, C., Kasprzycka, M., Szymczak, G., & Szewczyk, K. (2018). Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoë species. Saudi Journal of Biological Sciences, 25(4), 622–630. https://doi.org/10.1016/j.sjbs.2016.01.037
Delgadillo, L., Bañuelos, R., Delgadillo, O., Silva, M., & Gallegos, P. (2017). Composición química y efecto antibacteriano in vitro de extractos de Larrea tridentata, Origanum vulgare, Artemisa ludoviciana y Ruta graveolens. Nova Scientia, 9(19), 273. https://doi.org/10.21640/ns.v9i19.1019
Ebere Okwu, D., & Uchenna Nnamdi, F. (2011). A Novel Antimicrobial Phenanthrene Alkaloid from Bryopyllum pinnatum. Journal of Chemistry, 8(3), 1456–1461. https://doi.org/10.1155/2011/972359
García-Pérez, P., Miras-Moreno, B., Lucini, L., & Gallego, P. P. (2021). The metabolomics reveals intraspecies variability of bioactive compounds in elicited suspension cell cultures of three Bryophyllum species. Industrial Crops and Products, 163, 113322. https://doi.org/10.1016/j.indcrop.2021.113322
Kolodziejczyk-Czepas, J., Nowak, P., Wachowicz, B., Piechocka, J., Głowacki, R., Moniuszko-Szajwaj, B., & Stochmal, A. (2016). Antioxidant efficacy of Kalanchoe daigremontiana bufadienolide-rich fraction in blood plasma in vitro. Pharmaceutical Biology, 54(12), 3182–3188. https://doi.org/10.1080/13880209.2016.1214740
Kolodziejczyk-Czepas, J., & Stochmal, A. (2017). Bufadienolides of Kalanchoe species: An overview of chemical structure, biological activity and prospects for pharmacological use. Phytochemistry Reviews, 16(6), 1155–1171. https://doi.org/10.1007/s11101-017-9525-1
Marchev, A. S., Yordanova, Z. P., & Georgiev, M. I. (2020). Green (cell) factories for advanced production of plant secondary metabolites. Critical Reviews in Biotechnology, 40(4), 443–458. https://doi.org/10.1080/07388551.2020.1731414
Medina, J. J. (2017). Los otros ojos del cáncer. Lantia.
Pal, D. (with Nayak, A. K.). (2021). Bioactive Natural Products for Pharmaceutical Applications. Springer International Publishing AG.
Richwagen, N., Lyles, J. T., Dale, B. L. F., & Quave, C. L. (2019). Antibacterial Activity of Kalanchoe mortagei and K. fedtschenkoi Against ESKAPE Pathogens. Frontiers in Pharmacology, 10, 67. https://doi.org/10.3389/fphar.2019.00067
Stefanowicz-Hajduk, J., Hering, A., Gucwa, M., Sztormowska-Achranowicz, K., Kowalczyk, M., Soluch, A., & Ochocka, J. R. (2022). An In Vitro Anticancer, Antioxidant, and Phytochemical Study on Water Extract of Kalanchoe daigremontiana Raym.-Hamet and H. Perrier. Molecules, 27(7), 2280. https://doi.org/10.3390/molecules27072280
Thiago, J. D. S. B., Andréa, F. F., Ana, C. D. P. R. I., & Norma, A. (2016). Cytotoxic, antibacterial and antibiofilm activities of aqueous extracts of leaves and flavonoids occurring in Kalanchoe pinnata (Lam.) Pers. Journal of Medicinal Plants Research, 10(41), 763–770. https://doi.org/10.5897/JMPR2016.6260
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Elizabeth Nelly Paitan Anticona, Doris Marmolejo Gutarra, Libia Gutiérrez Gonzales, Alejandrina Sotelo Mendez, Javier Cordova Ramos

This work is licensed under a Creative Commons Attribution 4.0 International License.





